PSY40 EXTENDED-RELEASE OXYMORPHONE IS ASSOCIATED WITH LOWER SUBJECTIVE MONETARY VALUE THAN CONTROLLED-RELEASE OXYCODONE IN NONDEPENDENT RECREATIONAL OPIOID USERS
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چکیده
منابع مشابه
Bioequivalence of oxymorphone extended release and crush-resistant oxymorphone extended release
BACKGROUND A formulation of crush-resistant extended-release opioids may deter abuse. The purpose of this study was to evaluate the bioequivalence of oxymorphone extended-release (Oxy-ER) and a crush-resistant formulation of oxymorphone extended-release (Oxy-CRF). METHODS In three open-label, randomized studies, healthy adults at a clinical research center received two single oral doses of Ox...
متن کاملAbuse Potential with Oral Route of Administration of a Hydrocodone Extended-Release Tablet Formulated with Abuse-Deterrence Technology in Nondependent, Recreational Opioid Users
Objective To compare the oral abuse potential of hydrocodone extended-release (ER) tablet developed with CIMA ® Abuse-Deterrence Technology with that of hydrocodone immediate release (IR). Design Randomized, double-blind, placebo-controlled, crossover study. Setting and Patients One study site in the United States; adult nondependent, recreational opioid users. Methods After confirming th...
متن کاملA Comparison of Daily Average Consumption Of Oxycodone Controlled Release (OxyContin CR) And Oxymorphone Extended Release (Opana ER) In Patients With Low Back Pain.
OBJECTIVE Our goal was to examine the daily average consumption (DACON) of oxycodone controlled-release tablets (OxyContin CR)and oxymorphone extended-release tablets (Opana ER) in patients with low back pain. STUDY DESIGN An observational, retrospective cohort study enrolled patients with multiple prescriptions for oxycodone CR or oxymorphone ER tablets. These patients also had International...
متن کاملAbuse Potential of Intravenous Oxycodone/Naloxone Solution in Nondependent Recreational Drug Users
BACKGROUND AND OBJECTIVE Abuse of opioid analgesics has become a public health issue. Some opioid abusers use intravenous administration to increase the magnitude of positive reinforcing effects. Intravenous co-administration of oxycodone with naloxone, an opioid antagonist, may reduce these rewarding effects and discourage abuse. A 2:1 oxycodone:naloxone (OXN) tablet formulation has been studi...
متن کاملMaximizing value in opioid utilization: Is oxycodone immediate release a good option for pain management?
The modern approach to the management of pain involves optimizing all aspects of the process. This includes utilization of pharmacologic and non-pharmacologic modalities, consideration of patient characteristics, proper matching of the physiology of the pain with the analgesic's mechanism of action (pharmacodynamics, PD), and the onset and duration of action (pharmacokinetics, PK). No single ag...
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ژورنال
عنوان ژورنال: Value in Health
سال: 2010
ISSN: 1098-3015
DOI: 10.1016/s1098-3015(10)73042-4